该技术报告建议将深卷卷神经网络用作初步的诊断方法，用于分析来自严重急性呼吸系统症状（SARS）症状的胸部计算机断层扫描图像（SARS）和怀疑的Covid-19疾病，尤其是在延迟时在RT-PCR结果和缺乏紧急护理的情况下，可能会导致严重的暂时，长期或永久性健康损害。该模型接受了83,391张图像的培训，并在15,297张验证，并在22,185个数字上进行了测试，在Cohen's Kappa中获得了98％的F1分数，准确性98.4％，损失为5.09％。与当前的金色标准检查，实时反向转录酶聚合酶链反应（RT-PCR）相比，证明高度准确的自动分类并提供的时间更少。 - o存在相关性\'orio t \'ecnico prop \ 〜oe a fituiliza \ c {c} \ 〜ao de uma de uma de uma de uma de uma de uma de uma rede refolucional refolucional profunda como m \'etodo' tomografia computadorizada tor \'accica em pacientes com sintomas de s \'indrome respirat \'oria aguda grave（srag） ^encia de cuidados ungratees poderia acartar graves danos temer \'arios，\`longo prazo，ou permanentes \ a a sa \'ude。 o Modelo Foi Treinado EM 83.391成像，VILEDADO EM 15.297，E TESTADO EM 22.185 FIGURAS，ATINGINDO PONTUA \ C {C} \ 〜AO no F1-SCORE DE 98％，97,59％EM COHEN KAPPA，98,4％DEACUR，98,4％DEACUR \'acia e 5,09％损失。 atestando uma classifica \ c {c} \ 〜ao aumatizada r \'apida e de alta precis \ 〜ao，e fornecendo resuldo exultado em tempo menor ao ao do exame padr \ 〜Ao-ao-outo atual，o实时反向转移酶聚合酶链链反应（RT-PCR）。

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually updated with data from the physical systems to reflect its changing behaviour. For resource-constrained systems, updating a DT is non-trivial because of challenges such as on-board learning and the off-board data transfer. This paper presents a framework for updating data-driven DTs of resource-constrained systems geared towards system health monitoring. The proposed solution consists of: (1) an on-board system running a light-weight DT allowing the prioritisation and parsimonious transfer of data generated by the physical system; and (2) off-board robust updating of the DT and detection of anomalous behaviours. Two case studies are considered using a production gas turbine engine system to demonstrate the digital representation accuracy for real-world, time-varying physical systems.

Selecting the number of topics in LDA models is considered to be a difficult task, for which alternative approaches have been proposed. The performance of the recently developed singular Bayesian information criterion (sBIC) is evaluated and compared to the performance of alternative model selection criteria. The sBIC is a generalization of the standard BIC that can be implemented to singular statistical models. The comparison is based on Monte Carlo simulations and carried out for several alternative settings, varying with respect to the number of topics, the number of documents and the size of documents in the corpora. Performance is measured using different criteria which take into account the correct number of topics, but also whether the relevant topics from the DGPs are identified. Practical recommendations for LDA model selection in applications are derived.

Training agents via off-policy deep reinforcement learning (RL) requires a large memory, named replay memory, that stores past experiences used for learning. These experiences are sampled, uniformly or non-uniformly, to create the batches used for training. When calculating the loss function, off-policy algorithms assume that all samples are of the same importance. In this paper, we hypothesize that training can be enhanced by assigning different importance for each experience based on their temporal-difference (TD) error directly in the training objective. We propose a novel method that introduces a weighting factor for each experience when calculating the loss function at the learning stage. In addition to improving convergence speed when used with uniform sampling, the method can be combined with prioritization methods for non-uniform sampling. Combining the proposed method with prioritization methods improves sampling efficiency while increasing the performance of TD-based off-policy RL algorithms. The effectiveness of the proposed method is demonstrated by experiments in six environments of the OpenAI Gym suite. The experimental results demonstrate that the proposed method achieves a 33%~76% reduction of convergence speed in three environments and an 11% increase in returns and a 3%~10% increase in success rate for other three environments.

Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon these advances by designing a novel deep learning architecture consisting of a 3-dimensional convolutional neural network utilizing channel-wise attention and two graph convolutional networks utilizing attention-based aggregation of node features. HAC-Net (Hybrid Attention-Based Convolutional Neural Network) obtains state-of-the-art results on the PDBbind v.2016 core set, the most widely recognized benchmark in the field. We extensively assess the generalizability of our model using multiple train-test splits, each of which maximizes differences between either protein structures, protein sequences, or ligand extended-connectivity fingerprints. Furthermore, we perform 10-fold cross-validation with a similarity cutoff between SMILES strings of ligands in the training and test sets, and also evaluate the performance of HAC-Net on lower-quality data. We envision that this model can be extended to a broad range of supervised learning problems related to structure-based biomolecular property prediction. All of our software is available as open source at https://github.com/gregory-kyro/HAC-Net/.

Counterfactual explanation is a common class of methods to make local explanations of machine learning decisions. For a given instance, these methods aim to find the smallest modification of feature values that changes the predicted decision made by a machine learning model. One of the challenges of counterfactual explanation is the efficient generation of realistic counterfactuals. To address this challenge, we propose VCNet-Variational Counter Net-a model architecture that combines a predictor and a counterfactual generator that are jointly trained, for regression or classification tasks. VCNet is able to both generate predictions, and to generate counterfactual explanations without having to solve another minimisation problem. Our contribution is the generation of counterfactuals that are close to the distribution of the predicted class. This is done by learning a variational autoencoder conditionally to the output of the predictor in a join-training fashion. We present an empirical evaluation on tabular datasets and across several interpretability metrics. The results are competitive with the state-of-the-art method.

We describe a Physics-Informed Neural Network (PINN) that simulates the flow induced by the astronomical tide in a synthetic port channel, with dimensions based on the Santos - S\~ao Vicente - Bertioga Estuarine System. PINN models aim to combine the knowledge of physical systems and data-driven machine learning models. This is done by training a neural network to minimize the residuals of the governing equations in sample points. In this work, our flow is governed by the Navier-Stokes equations with some approximations. There are two main novelties in this paper. First, we design our model to assume that the flow is periodic in time, which is not feasible in conventional simulation methods. Second, we evaluate the benefit of resampling the function evaluation points during training, which has a near zero computational cost and has been verified to improve the final model, especially for small batch sizes. Finally, we discuss some limitations of the approximations used in the Navier-Stokes equations regarding the modeling of turbulence and how it interacts with PINNs.

Despite their impressive performance on diverse tasks, large language models (LMs) still struggle with tasks requiring rich world knowledge, implying the limitations of relying solely on their parameters to encode a wealth of world knowledge. This paper aims to understand LMs' strengths and limitations in memorizing factual knowledge, by conducting large-scale knowledge probing experiments of 10 models and 4 augmentation methods on PopQA, our new open-domain QA dataset with 14k questions. We find that LMs struggle with less popular factual knowledge, and that scaling fails to appreciably improve memorization of factual knowledge in the tail. We then show that retrieval-augmented LMs largely outperform orders of magnitude larger LMs, while unassisted LMs remain competitive in questions about high-popularity entities. Based on those findings, we devise a simple, yet effective, method for powerful and efficient retrieval-augmented LMs, which retrieves non-parametric memories only when necessary. Experimental results show that this significantly improves models' performance while reducing the inference costs.

We introduce the Conditional Independence Regression CovariancE (CIRCE), a measure of conditional independence for multivariate continuous-valued variables. CIRCE applies as a regularizer in settings where we wish to learn neural features $\varphi(X)$ of data $X$ to estimate a target $Y$, while being conditionally independent of a distractor $Z$ given $Y$. Both $Z$ and $Y$ are assumed to be continuous-valued but relatively low dimensional, whereas $X$ and its features may be complex and high dimensional. Relevant settings include domain-invariant learning, fairness, and causal learning. The procedure requires just a single ridge regression from $Y$ to kernelized features of $Z$, which can be done in advance. It is then only necessary to enforce independence of $\varphi(X)$ from residuals of this regression, which is possible with attractive estimation properties and consistency guarantees. By contrast, earlier measures of conditional feature dependence require multiple regressions for each step of feature learning, resulting in more severe bias and variance, and greater computational cost. When sufficiently rich features are used, we establish that CIRCE is zero if and only if $\varphi(X) \perp \!\!\! \perp Z \mid Y$. In experiments, we show superior performance to previous methods on challenging benchmarks, including learning conditionally invariant image features.

Most TextVQA approaches focus on the integration of objects, scene texts and question words by a simple transformer encoder. But this fails to capture the semantic relations between different modalities. The paper proposes a Scene Graph based co-Attention Network (SceneGATE) for TextVQA, which reveals the semantic relations among the objects, Optical Character Recognition (OCR) tokens and the question words. It is achieved by a TextVQA-based scene graph that discovers the underlying semantics of an image. We created a guided-attention module to capture the intra-modal interplay between the language and the vision as a guidance for inter-modal interactions. To make explicit teaching of the relations between the two modalities, we proposed and integrated two attention modules, namely a scene graph-based semantic relation-aware attention and a positional relation-aware attention. We conducted extensive experiments on two benchmark datasets, Text-VQA and ST-VQA. It is shown that our SceneGATE method outperformed existing ones because of the scene graph and its attention modules.